Dengue and multiple osteonecrosis of the maxilla and mandible: a case report
Article Sidebar
Main Article Content
Abstract
Dengue is a viral disease transmitted by Aedes aegypti mosquitoes that has recently experienced a significant increase in incidence. This report presents an unusual case of osteonecrosis affecting both the upper and lower jaw in a young patient without a history of pathological or medication exposure before contracting dengue virus infection.
Similar to other viral diseases associated with maxillary osteonecrosis, Dengue induces endothelial inflammation that triggers a series of events leading to thrombosis and necrosis of bone tissue.
Considering that the increase in dengue cases is linked to climate change, it is plausible to speculate that dengue will become more frequent in the future, as well as its association with osteonecrosis.
Article Details
Derechos de autor: Actualizaciones en Osteología es la revista oficial de la Asociación Argentina de Osteología y Metabolismo Mineral (AAOMM) que posee los derechos de autor de todo el material publicado en dicha revista.
References
Ministerio de Salud de la República Argentina. Boletín Epidemiológico Nacional N.° 695. 2024. ttps://bancos.salud.gob.ar/recurso/boletin-epidemiologico-nacional-n-695-se-10-2024
Anderson JR, Rico-Hesse R. La capacidad vectorial de Aedes aegypti está determinada por el genotipo infectante del virus del dengue. Am J Trop Med Hyg. 2006;75(5):886-92.
Pomeranz M, Kessler E, Kessler A. Osteonecrosis: pathophysiology, diagnosis, and treatment. J Bone Joint Surg Am. 2020;102(10):895-906.
Khan AA, Morrison A, Hanley DA, et al. Osteonecrosis of the jaw: a systematic review and meta-analysis. J Bone Miner Res. 2017;32(6):1242-50.
Aghaloo T, Moy PK. Osteonecrosis of the jaws: a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2007;103(1):1-10.
Ruggiero SL, Dodson TB, Fantasia J, et al. Osteonecrosis of the jaw: a systematic review and guidelines for diagnosis and management. J Oral Maxillofac Surg. 2006;64(5):1-25.
Gollapudi K, et al. Osteonecrosis of the jaw and its association with antiretroviral therapy in HIV-infected patients: a case-control study. J Oral Maxillofac Surg. 2020;78(5):825-32.
Khan MA, Rahman T, Rahman SA, et al. Is post-COVID osteonecrosis of the jaw (PCONJ) masquerading as osteomyelitis? A largest unicentric report of 13 cases. Adv Oral Maxillofac Surg. 2023;11:100435. doi:10.1016/j.adoms.2023.100435.
Slavkova N, Nedevska M. Aseptic osteonecrosis of the maxilla after severe COVID-19 infection and its treatment. Radiol Case Rep. 2022;17(9):3228-32. doi:10.1016/j.radcr.2022.06.009.
Mañón VA, Balandran S, Young S, et al. COVID-associated avascular necrosis of the maxilla—a rare, new side effect of COVID-19. J Oral Maxillofac Surg. 2022;80(7):1254-9. doi:10.1016/j.joms.2022.04.015.
Park K-S. Maxillary osteonecrosis related with herpes zoster: a case report and review of the literature. Medicina. 2024;60:883. doi:10.3390/medicina60060883.
Yogesh TL, Jahagirdar A, Jagadeesh RB, Ghosh D. Avascular necrosis of maxilla: a rare case report with a review. J RGUHS Med Sci. 2017;7(1):16-20.
Indurkar MS, Sethi R. An unusual case of osteonecrosis of the jaw associated with dengue fever and periodontitis. Aust Dent J. 2016;61(1):113-9. doi:10.1111/adj.12308.
Patil PP, Bhavthankar JD, Mandale MS, Humbe JG. Jaw osteonecrosis preceded by dengue fever—possible pathogenetic mechanism. J Orthop Case Rep. 2018;8(6):9-12. doi:10.13107/jocr.2250-0685.1234.
Malavige GN, Ogg GS. Patogenia de la fuga vascular en la infección por el virus del dengue. Inmunología. 2017;151(3):261-9. doi: 10.1111/imm.12748.
Wang J, Zhuang H, Zhang Y, et al. The role of cytokines in the pathogenesis of dengue virus infection. Cytokine. 2020;136:155298. doi:10.1016/j.cyto.2020.155298.
Dirección de Epidemiología de Mendoza. Reporte Epidemiológico Anual de Dengue. 2023. https://www.mendoza.gov.ar/salud/reporte-epidemiologico