Polyostotic Pagets disease resistance tobiphosphonatestreated with denosumab. Case report

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Vanina Soledad Farías
María Belén Zanchetta

Abstract

A case of a 85 years old woman with polyostotic Paget's disease treated with bisphosphonates for several years (pamidronate, zoledronate and ibandronate) is presented. However, after the schemes received persisted with active disease, clinically symptomatic and high bone alkaline phosphatase, then was decided to indicate an alternative antiresorptive treatment with denosumab.and good therapeutic response and without adverse effects.

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Case Reports

How to Cite

1.
Polyostotic Paget’s disease resistance tobiphosphonatestreated with denosumab. Case report. Actual. Osteol. [Internet]. 2024 Jul. 9 [cited 2026 Oct. 10];10(3):290-7. Available from: https://ojs.osteologia.org.ar/aaomm/index.php/osteologia/article/view/401

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