IMPACT OF RENAL INSUFFICIENCY ON FLUORIDE METABOLISM

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RODOLFO C. PUCHE
ALFREDO RIGALLI

Abstract

Renal insufficiency brings about cumulation of fluoride in bone mineral and joints. Healthy subjects excrete 50% of fluoride intaken through renal excretion. The latter can fall as low as 6% in chronically renal insuficient patients. Often, the latter exhibit polydipsia (secondary to polyuria) which increases water intake (and fluoride exposition). In countries where fluorosis is endemic (e.g.: India) the use of distilled water is advocated for hydration or dyalisis of renal insufficient patients.

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IMPACT OF RENAL INSUFFICIENCY ON FLUORIDE METABOLISM. Actual. Osteol. [Internet]. 2024 Jul. 22 [cited 2026 Oct. 11];3(1):49. Available from: https://ojs.osteologia.org.ar/aaomm/index.php/osteologia/article/view/585

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